Biotoxin pathway shoemaker. He’s really changed my life.

Biotoxin pathway shoemaker. It essentially shows the pathway of harm and dysfunction that toxic mold causes in the body. gov/members/2003/5478/5478. The CIRSx mission is to transform multiple industries, revolutionizing their approaches toward Chronic Inflammatory Response Syndrome (CIRS) and other environmentally related health challenges. Karen Johnson, MD: what is CIRS, can CIRS be cured? Biotoxin illness exposure, symptoms, testing, and more. The Biotoxin Pathway Introduction to “Excerpts from Dr. Find out what chronic inflammatory response syndrome is, how people get exposed, and who is susceptible. This recognition and binding of the biotoxin causes a continual upregulation of multiple inflammatory pathways, including production of cytokines, split product of complement, and TGF 1. Surviving Mold. Nov 13, 2018 · In part 2 of a series on Mold-Related Biotoxin Illness (or Chronic Inflammatory Response Syndrome), Dr. Shoemaker was selected as Physician of the Year in the state where he practiced medicine for his valuable contributions in finding the cause of some devastating environmental illnesses. Sep 11, 2024 · Today's guest is Dr. He’s written several books, including “Mold Warriors,” and also “Surviving Mold,” Joe calls that one my bible. What Are the CIRS Blood Markers? The first lab test needed is the HLA-DR which identifies the genetic susceptibility to CIRS. Not all patients will require all steps. In fact, Dr Shoemaker has found that 95% of his biotoxin illness patients have one or more of these defective genes. Jenski and I broke down the intricate biotoxin pathway that characterizes Chronic Inflammatory Response Syndrome (CIRS). It systematically targets the complex effects of biotoxin illness by focusing on the underlying inflammatory pathways that contribute From Our Third Annual Provider's Conference from October 2016 in Irvine, CA Keith Berndston, MD Biotoxin Pathway 2. Jul 24, 2024 · In this episode, Dr. Shoemaker developed a protocol based on the pathway biotoxins take in genetically susceptible people. Apr 20, 2024 · The biotoxin pathway explains why CIRS is a multi-system, multi-symptom condition, you can learn more about the biotoxin pathway here. CIRS, a multi-system, multi-symptom chronic illness, arises when the immune system is Mar 18, 2025 · How could staring at blurry lines possibly explain your fatigue and constant aches? Learn what a CIRS eye test reveals about your health. Shoemaker’s argument that the reason people get CIRS is due to an inability to make antibodies to Biotoxins is a very thinly supported theory. Ritchie Shoemaker, MD, who is a world renowned expert in the field of biotoxin illness who first described CIRS, we now Plug the patient into the Biotoxin Pathway; follow the order of treatment that Dr. Ritchie Shoemaker, who many call the Father of Mold Medicine, who is one of Dr. Mar 25, 2024 · This is due to the differences in how someone processes the mycotoxins through the biotoxin pathway, as proposed by Dr. Feb 9, 2023 · -The Evolution of CIRS (Chronic Inflammatory Response Syndrome and The Biotoxin Pathway. Learn about the groundbreaking Shoemaker Protocol and reclaim your health today. In genetically susceptible people, biotoxins bind to pattern receptors, HIF Reduced VEGF leads to fatigue, muscle cramps, and causing continuing, unregulated production of cytokines. ; Medical Director at the Center for Research on Biotoxin Associated Illnesses; and has a private practice in Pocomoke, Maryland. What about the 75% who aren’t genetically susceptible to mold/biotoxin illness? olerate excessive toxic mold exposure. Chronic Inflammatory Response Syndrome (CIRS) Carnivore and CIRS The Body’s Toxic Load Shoemaker Protocol Biotoxins and the Biotoxin Pathway CIRS Diagnosis Binders Mycotoxin Tests vs. It was the missing piece that she had been searching for since the beginning of her career in medicine. is packed with colorful diagrams and tables for easier Shoemaker Protocol: Treatment Treatment for biotoxin illness can begin once the patient is removed from the source of mold. Jul 28, 2025 · This shift was marked by the publication of the first formal case definition of chronic biotoxin-associated illness in 2005 [24]. Ritchie Shoemaker, and the topic of the show is GENIE Testing in CIRS. Transcriptomics can provide a unique fingerprint for the subtypes of CIRS, confirm hypometabolism and even tailor treatment for the individual. The idea is that these treatment steps are similar to how one would climb a pyramid. It is the only peer-reviewed, clinically replicable treatment for biotoxin illnesses, including mold illness, grounded in rigorous scientific research and clinical trials, ensuring its Mold is a HUGE problem here in Seattle. Shoemaker’s daily practice, other illnesses caused by exposure to May 13, 2024 · Biotoxin illness, often triggered by exposure to mold, is becoming increasingly recognized as a significant health concern. Most of what we know about this condition is the result of practice-based studies done by physician-researcher Ritchie Shoemaker. Sep 22, 2004 · Subject: [] Dr Shoemaker Congressional Testimony Stand by for news! Dr Shoemaker has been invited by Congressman Conyers to speak before Congress on his work regarding the Biotoxin Pathway and mold exposure. Sandeep Gupta and pediatrician Dr. The Shoemaker Protocol identifies those sickened from biotoxin illness and uses rigorously tested interventions to help them recover. CIRS is an acronym for Chronic Inflammatory Response Syndrome which describes a pathological response to toxic substances that are found in mold and mycotoxins. Member Q&A January 2025Week of Jan 15 1/ Biotoxin Binders QUESTION: My primary physician has prescribed Pectasol for my wife who has early onset dementia, felt to be due to biotoxin exposure. Mar 22, 2020 · It was Dr. Mar 30, 2017 · Mold Illness can be diagnosed as chronic fatigue, depression, fibromyalgia, MS, lupus, Lyme disease, inflammatory bowel disease, irritable bowel, etc. • Causes inflammation to gastrointestinal linings as well as the urinary and biliary tract • Damages the liver, gallbladder, and kidneys • Results in cholestasis and Ritchie Shoemaker, M. Sick Building Syndrome: Another Stop Along the Biotoxin Pathway Maryland College of Occupational and Environmental Medicine, Johns Hopkins 12/04/2004 According to Dr. See full list on richmondfunctionalmedicine. The Shoemaker Protocol is an evidence-based approach to biotoxin illness. Shoemaker first began using it. , mold May 8, 2024 · The biotoxin pathway explains why CIRS is a multi-system, multi-symptom condition, you can learn more about the biotoxin pathway here. May 31, 2007 · Article: Biotoxin Pathway Holds Key Pieces of Puzzle in Solving Chronic Illness Publication: Public Health Alert / June 2007 Summary: A look at Dr. This test correlates with the Nov 9, 2007 · Ritchie C. Shoemaker, MD, April Vukelic, DO -The Shoemaker Protocol. Jul 20, 2021 · Dr. Jun 10, 2009 · Using various tests, Dr. Personalized protocols, including ERMI testing and ADH regulation, are critical for long-term healing. states . Shoemaker is the only clinically proven, peer-reviewed treatment for mold illness and has treated tens of thousands of patients worldwide. com. Ritchie Shoemaker, MD's "Biotoxin Pathway" Check out the image above showing the biotoxin pathway coined by Dr. Shoemaker is describing the biotoxin pathway. Molds are ubiquitous in the environment, and while they play an essential part in the ecosystem by breaking down organic matter, they can also pose dangers to human health. com 5/30/16 8 The Biotoxin Pathway High levels of cytokines produce flu-like symptoms: Headaches, muscle aches, fatigue, unstable temperature, difficulty concentrating and more. Aug 1, 2025 · How We Diagnose and Treat It Our team is trained to recognize the complex presentation of biotoxin illness. com Protocol Overview: What to Expect At its core, Dr. He’s really changed my life. Ritchie Shoemaker, represents a paradigm change in the treatment of biotoxin illness, including mold illness. The key to diagnosing and monitoring the presence of biotoxins in the system is the Visual Contrast Sensitivity (VCS test). Testing, solutions, evidence, and more. Many conditions have symptom overlap. Sarah shares her experience being diagnosed with CIRS, and reviews the Dr. The biotoxin pathway explains why CIRS is a multi-system, multi-symptom condition, you can learn more about the biotoxin pathway here. Ritchie Shoemaker on the latest in GENIE testing, molecular hypometabolism and inflammation-driven by Actinomyces, endotoxins and mold or other toxic exposures. Shoemaker is a pioneer in understanding how low-dose biotoxin exposure, including toxic mold and algae, impacts our health and contributes to disease. Finally, a good explanation for why everyone isn’t as sick as some. The Biotoxin Pathway The Biotoxin Pathway (large clear version) diagram sums up CIRS nicely. Chronic Inflammatory Response Syndrome was a description coined by Ritchie Shoemaker, MD, to describe The Shoemaker Protocol is the leading treatment protocol, developed by Dr. For those struggling with Lyme disease or other chronic illnesses, understanding the numerous impacts of biotoxins, toxic substances produced by living organisms, may be the key to an improved state of health and well-being. Smith as a practicing physician herself. After hearing Dr. CIRS, when caused by a water-damaged building, is more commonly known as Mould Illness (Mold Illness The Biotoxin Pathway High cytokine levels in the capillaries attract white blood cells, leading to restricted blood flow, and lower Capillaries oxygen levels. Outlined in three key stages, this method emphasizes removal from biotoxin Dr. Nov 25, 2016 · “The visual system is the ideal place to look for evidence of neurotoxicity,” says Hilton Kenneth Hudnell, PhD, the first scientist to use it to measure the effects of biotoxin exposure and heavy metal toxicity, or as a marker for neurotoxic exposures like Pfiesteria. Ritchie Shoemaker Biotoxin Pathway that manifests in the body once CIRS is triggered. com Frequently Asked Questions, including screening and diagnosing Mould Illness/CIRS (symptoms, VCS, blood biomarkers, NeuroQuant), the CIRS (Shoemaker) treatment protocol (mold avoidance, binders, MARCoNS, VIP), building testing (ERMI, HERTSMI-2, IEP), and the basics of building remediation. His protocol identifies key steps in the inflammatory response and offers structured treatment pathways. HIF stimulates VEGF and TGF B-1. High levels of cytokines also result in increased levels of several other immune-response related substances, including TGF B-1, MMP-9, IL-1B, and PAI-1. Suite 500 Pocomoke, MD 21851 410-957-1550 phone 410-957-3930 fax ritchieshoemaker@msn. Shoemaker’s lecture on Chronic Inflammatory Response Syndrome (CIRS), mold illness, and the biotoxin pathway. There are different steps that The Biotoxin Pathway has provided a template to understand how CIRS disrupts neuroregulatory pathways, coagulation factors and T regulatory cells. When exposed to mold, the adaptive immune system, responsible for producing antibodies, fails to recognize and Article: Biotoxin Pathway Holds Key Pieces of Puzzle in Solving Chronic Illness Publication: Public Health Alert / June 2007 Summary: A look at Dr. There is no data published anywhere showing benefit of Pectasol as a replacement for cholestyramine and Welchol, the medication used as a binder in an initial Shoemaker May 12, 2023 · Sarah shares her experience being diagnosed with CIRS, and reviews the Dr. Congressman Conyers introduces mold bill HR 1268. The Biotoxin Pathway When exposed to the microbes, toxins and inflammagens associated with water-damaged buildings or other biotoxin-producing organisms, a series of complex biochemical events begins. May 10, 2024 · The biotoxin pathway explains why CIRS is a multi-system, multi-symptom condition, you can learn more about the biotoxin pathway here. That makes the Visual Contrast Sensitivity (VCS) Test one of the most accurate screening tools in medicine for detecting mold-related biotoxin illness. May 12, 2023 · Chronic Inflammatory Response Syndrome (CIRS): Who's Affected, How To Test For It + What To Do Next This episode is all about CIRS: Chronic Inflammatory Response Syndrome. The Biotoxin Pathway is a brilliantly conceived tool by Dr Shoemaker and has been invaluable in my practice both for patient education and practitioner training since many of my patients are physicians themselves. Shoemaker's CIRS treatment protocol is complex and unique to each patient. Shoemaker recommends that if a patient has symptoms present in 6 or more of the symptom clusters, biotoxin illness is possible and further testing and evaluation must be done. Shoemaker. Follow electrolytes (CMP) and Dr. Plug the patient into the Biotoxin Pathway; follow the order of treatment that Dr. Shoemaker has performed prospective trials and published his protocol in peer reviewed journals. Australian Government response to the Inquiry into Biotoxin-related Illnesses in Australia. Ritchie C. Found in all known forms of life, it is often referred to as the "molecular unit of currency " for intracellular energy transfer. Shoemaker’s Approach To ensure the best chance at knocking out MARCoNS, you need to complete the first two steps of Dr. Mar 14, 2021 · In Shoemaker’s development of a CIRS treatment protocol, a “pathway” by which biotoxin illness progressed was charted. The Myco-Toxicity Cycle. Risk is understood at this point to be highly associated with HLA type, rendering some people more at-risk than others for environmental-related illness. VCS test/s are included (amount depends on membership type). g. American Journal of Case Reports 2016:320-325. Shoemaker’s knowledge of biotoxin pathways that really played a huge part in my recovery. The Biotoxin Pathway is the best summary of Dr. Every step is peer-reviewed, and it is a structured, step-by-step method that relies on well-designed studies. survivingmold. LOG IN / GET STARTED >> The Shoemaker Protocol™ VCS online screening system is relied upon by certified Shoemaker Protocol™ Practitioners & Partners, patients, healthcare professionals, and researchers all Chronic Inflammatory Response Syndrome Explained Chronic Inflammatory Response Syndrome (CIRS) is a multi-system, multi-symptom illness caused by inhaling biotoxins and inflammagens produced by micro-organisms such as mould, bacteria, and actinomycetes found in water-damaged buildings (WDB). Shoemaker didn't just name the problem; he built a pathway out for biotoxic illness. Ritchie Shoemaker, M. Editor, Bioaerosols, Fungi. I'm very excited about Dr. Nov 29, 2023 · They might have had CIRS before Dr. Shoemaker’s Protocol for Chronic Inflammatory Response Syndrome In our last article, we talked about how CIRS affects your body, and why it is so often overlooked or misdiagnosed. Sep 25, 2024 · The Shoemaker Protocol is a comprehensive, step-by-step treatment plan developed by Dr. Feb 27, 2023 · Enjoy 217. Introduction to Chronic Inflammatory Response Syndrome (CIRS) - Carnivore and CIRS from Nutrition with Judy on Everand. Surviving mold requires that you become knowledgeable about how to protect yourself from it. Richie Shoemaker, pioneer and visionary in the field of Chronic Inflammatory Response Syndrome (CIRS), has been researching the subject for 18 years. They are unable to process the biotoxin and that leads to a series of biochemical alterations called the Biotoxin Pathway. Your pyramid will be the one that returns you to pre-mould wellness. Shoemaker, R. Shoemaker has provided a pathway chart depicting the effects of biotoxins on genetically susceptible people and the varied responses the body may engender to combat the insult. We explored how biotoxins from various sources (e. Aug 24, 2025 · Dr. Shoemaker’s biotoxin pathway (Shoemaker, 2011) to my physician, and asked for testing and treatment. Shoemaker R, Rash J, Simon E. Nov 20, 2023 · The Shoemaker Protocol is an 11-step approach that addresses each corresponding stage of the biotoxin pathway in order to correct all of the consequences caused by WDB mold exposure. You can work with us to get started on the Shoemaker protocol. Jun 3, 2024 · Explore the complexities of Chronic Inflammatory Response Syndrome (CIRS) and the biotoxin pathway. I recently had the opportunity to sit down and discuss this exciting area of research with Dr. Jan 22, 2025 · Ritchie Shoemaker, MD is a recognized leader in patient care, research, and an education pioneer in the field of biotoxin related illness. Berndtson Are Mold Biotoxins Making You Fatigued and Sick by Dr. C4a, TGF-b1 & more. TGF B-1 changes cell type and interacts with Treg cells. This recognition and binding of the biotoxin causes a continual upregulation of multiple inflammatory pathways, including production of cytokines, split product of complement, and TGFβ1. The Shoemaker Protocol is a thorough, evidence-based treatment plan developed by Dr. That doesn’t mean his protocol doesn’t work, but simply that the driver behind CIRS is unknown. Ritchie Shoemaker, a research pioneer in the field of biotoxin related illness, discovered the process that the bodies of CIRS patients go through: The Biotoxin Pathway. Now that the importance of the “Biotoxin Pathway” is understood, we shift focus to the interventions that can be put in place to improve one’s state of wellness. Ritchie Shoemaker sheds light on the genetic link to mold-related illnesses. This physician, a certified “Shoemaker” physician, was able to restore her health. (2011). Ritchie Shoemaker’s book, “Surviving Mold” Review of the Works of Dr. Start here: WELCOME, CIRS CLINIC AT HEALTH AND WELLNESS OF CARMEL My Shoemaker Protocol Paper -A Walk Through the Biotoxin Pathway 2018 Surviving Mold Medical Consensus Guidelines GAO_2008 Report Prescription Medications Dr. Ritchie Shoemaker and read his book Mold Warriors (Shoemaker, 2005). This Physician's If you find mold in your home, or suspect that mold or mycotoxin illness, where should you spend your money? Supplements? Testing? The Biotoxin illness pathway below: A detailed description of the progressive nature of CIRS Figure: The biotoxin illness pathway illustrates the progressive nature of CIRS (see Surviving Mold Biotoxin Pathway). html We compared the inflammatory and cyto Just what does mold do? How is it possibly affecting so many organs/systems in my body? Dr. I truly believe that the impact of his work in the field of This body of work explains the pathway through which these toxins impact biorhythms, sleep, antioxidant activity, and detoxification. Shoemaker’s treatment is designed to help the body eliminate biotoxins, and address imbalances caused by the biotoxins and the ongoing immune response. This is another key step of the biotoxin pathway and probably the most self-evident. The biotoxin pathway is outlined in the following diagram: Ritchie Shoemaker, M. Shoemaker, author of the above Biotoxin Pathway graphic. Ritchie Shoemaker’s Discovery of Chronic Inflammatory Response Syndrome (CIRS) Saved My Life and Why You Should Care Dr. Shoemaker’s work on the biotoxin pathway provides a comprehensive overview of biotoxin’s impact on the immune system and the steps for remission. [47] Commonwealth of Australia. Biotoxin Binders 419 likes, 51 comments - is_ibd_mold_toxicity on February 9, 2024: "This is an oversimplification. Shoemaker, MD Preview: Mar 27, 2016 · His grasp of the biotoxin pathway and the clarity it brings to our understanding these illnesses has brought healing to thousands of suffering patients. niehs. Step one it to make sure your home and work environments are mold free. Read about the biotoxin pathway and how these biotoxins travel through the human body causing mold illnesses. Chronic Inflammatory Response Syndrome by Dr. Ascending the pyramid step by step leaves a steadily smaller number of people with illness. Called the Biotoxin Pathway, this framework described the order in which multiple cells, glands, organs, and hormones are affected by lingering biotoxins. Results within minutes. Dec 17, 2023 · Dr. Jul 7, 2018 · Shoemaker and colleagues are generating a database of differential gene activation that will be a fingerprint for biotoxin illness and will help differentiate the root cause precipitating the Biotoxin Pathway. , is a recognized leader in patient care, research and education pioneer in the field of biotoxin related illness. Unfortunately, mycotoxins are linked to many chronic diseases, including: Autism Alzheimer’s and Parkinson’s Disease Chronic fatigue and fibromyalgia Asthma Fungal Sinusitis Multiple sclerosis Obesity The Biotoxin Pathway In genetically susceptible binds to receptors causing continuinynregulated production Of Cytokines Capillaries High cytokine levels in the capillaries attract White blood cells, leading to restricted blood floud lower oxygen levels Reduced VEGF leads to fatigueuscle and shortness 01 breatmay be overidden by replacement with Dr. Shoemaker’s Biotoxin Pathway (2005, 2011). This Physician's Consequently, for a significant number of people, biotoxin illness owing to ongoing mold exposure results in systemic and chronic bodily inflammation and a cascade of negative human health impacts. Discover symptoms, testing, and how to heal using functional medicine. This illness is called CIRS- chronic inflammatory response syndrome. The Biotoxin Pathway High cytokine levels in the capillaries attract white blood cells, leading to restricted blood flow, and lower Capillaries oxygen levels. But once you know you have CIRS, what can you do about it? Thanks to the research of Dr. While illness acquired following exposure to the interior environment of water-damaged buildings (WDB) comprises the bulk of Dr. Parliament of Australia. Oct 1, 2019 · Moldy Buildings, CIRS, Sick People, and Damaged Brains: 25 Years of Research Brought Us to the Cure Word, Part 3 Ritchie C. He is the President of Chronic Neurotoxins, Inc. In genetically susceptible people, biotoxins bind to pattern receptors, Dr. Jul 17, 2025 · However, it's important to note that CIRS can also be caused by biotoxin producers such as cyanobacteria and a marine dinoflagellate that produces the Ciguatera toxin found in certain types of fish. In cases of CIRS, the MBL pathway works overtime due ongoing inhalation and poor clearance of biosurface PAMPs, VOCs, and biotoxins from the air inside damp homes, workspaces, and/or schools. In a series of studies going back to 1998, Shoemaker developed an increasingly In 2006 I researched the work of Dr. Shoemaker’s protocol includes prescription medications to regulate inflammatory markers, support detoxification pathways, and modulate the immune system. Scott McMahon talk about the prevalence of Mold Illness/CIRS in children and how to adequately screen, diagnose and treat kids using the Shoemaker protocol and how CIRS and Autism interact. Your next steps include following up with a Shoemaker Protocol™ informed practitioner for diagnostic confirmation and treatment plan, plus you will need to locate the source of the mold problem (usually home, school, or work) and remediate and/or remove yourself from mold/biotoxin exposure. The Surviving Mold Protocol, developed by Dr. Sick Building Syndrome in water-damaged buildings: Generalization of the chronic biotoxin-associated illness paradigm to indoor toxigenic fungi in Johanning E. While illness acquired following exposure to the interior environment of water-damaged buildings (WDB) comprises the bulk of Shoemaker’s daily practice, other illnesses caused by exposure to biologically Apr 1, 2005 · By reading Mold Warriors, you will learn how to use the Biotoxin Pathway, a magnificent scientific and medical breakthrough, to then easily recognize and treat the mold illness, leavin! g behind meaningless diagnoses such as fibromyalgia, chronic fatigue, stress, “chronic pain syndrome,” deconditioning and more. It was just a year earlier that he had met Ritchie Shoemaker, when Ritchie had given a talk on his latest findings and a novel flow chart of pathology he called the “Biotoxin Pathway”. I highly recommend that you spend some time on the site to better understand how to evaluate and approach biotoxin-related illness (whether it be Lyme, Mold, or other biotoxins). Surviving mold illness begins with knowing whats wrong & developing a plan to beat it. The interactive version of the graphic ‘The Biotoxin Pathway’ is an approximate duplicate (corrections in spelling and modifications in presentation) of Shoemaker's graphic, except that specific objects within the graphic can be identified by an internet-based user, and information relative to that specific object (and specific point in a patient’s condition) can be offered via different Looking for a structured understanding of Dr. Lauren Sparks, DNP, CNP, APRN The Biotoxin Pathway High cytokine levels in the capillaries attract white blood cells, leading to restricted blood flow, and lower Capillaries oxygen levels. Shoemaker, 2011 Title Biotoxin Pathway_3_22_2011_color_background. Retrieved from www. It highlights that individuals with genetic predispositions, such as defective genes, are more susceptible to mold toxicity. Eliminating gluten for those with anti-gliadin positivity as shown Genetic Predisposition and Biotoxin Illness The Biotoxin Pathway developed by Dr. Shoemaker, if symptoms are present and the VCS test is positive — even in one eye — there’s a 98. Shoemaker graduated medical school from Duke University (1969-1973) Magna Cum Laude. In this chapter, Shoemaker and colleagues outlined a structured diagnostic approach based on a combination of symptom burden, objective laboratory abnormalities, and therapeutic response. Shoemaker named the constellation of symptoms Chronic Inflammatory Response Syndrome. I took the book and Dr. To achieve that, Dr. It can show the direct neurological affect of cytokines on the brain. Jan 27, 2013 · Chronic Fatigue Syndrome: Lessons from the Biotoxin Pathway 12/4/04 Johns Hopkins University, Occupational and Environmental Medicine Conference, Chronic Illness from Water-Damaged Buildings: Just Another Stop Along the Biotoxin Pathway This is due to the differences in how someone processes the mycotoxins through the biotoxin pathway, as proposed by Dr. Ryan, PhD Chief Science Officer, ProgeneDx Box/Shade Editor’s Note. If a biotoxin pathway is suspected, our team follows evidence-informed protocols that may include: Identifying and minimizing potential sources of exposure (e. Nov 6, 2014 · Dr. Medications like cholestyramine or Welchol are often prescribed to bind mycotoxins and remove them from the body. Shoemaker, MD This physician, a Shoemaker Protocol Certified Physician, was able to restore her health, which excited and intrigued Dr. Ritchie Shoemaker, in his groundbreaking book, published in 2005,groundbreaking book, published in 2005, Mold WarriorsMold Warriors, outlined the entire Biotoxin, outlined the entire Biotoxin Pathway, which provided clear guidelinesPathway, which provided clear guidelines of how to remove toxin from the body,of how to remove toxin from the body Founded in 1985, the AANP represents licensed naturopathic doctors, students, and allied healthcare professionals nationwide. But, like all new findings, this information does not yet constitute a “science”. The innate immune division includes a “Complement”system with Classical, Alternative, and MBL pathways that recognize and respond to PAMPs. Dr Shoemaker outlined the pattern of possible response via his Nov 5, 2011 · The only option for HLA types (meaning those HLA types that are susceptible to biotoxin illness based on Shoemaker's work) to eliminate toxins is the organic anion transport system in the small bile ducts of the liver to secrete the toxin into the bile. Created by Dr. While there are many practitioners, each with their own “proprietary” treatment plan, caring for these patients, only Dr. Shoemaker’s “Biotoxin Pathway” published in 2011 illustrates a concise model of how mold exposure in genetically susceptible people leads to sequential hyper-immune responses, which contribute to myriad manifestations of unwellness. Ritchie ShoemakerRitchie Shoemaker, M. Jun 1, 2007 · Using these markers, the diagnostic accuracy of the Shoemaker model is compelling. Biotoxin Pathway By Dr. When mold or biotoxins are not processed effectively, a series of biochemical changes known as the Biotoxin Pathway occur. C. [48] Shoemaker, R. Jun 3, 2005 · It says that bacteria should be considered as a cause of adverse inflammatory effects in water damaged buildingsthis is what Shoemaker says in the the Biotoxin Pathway http://ehp. Discover the Shoemaker Protocol - a pioneering approach for addressing Chronic Inflammatory Response Syndrome (CIRS). D. Although not specific for biotoxin burden is is a good screening tool for biotoxin illness and used in many practitioners practices. In genetically susceptible people, biotoxins bind to pattern receptors, Feb 21, 2025 · Dr. Unfortunately, mycotoxins are linked to many chronic diseases, including: Autism Alzheimer’s and Parkinson’s Disease Chronic fatigue and fibromyalgia Asthma Fungal Sinusitis Multiple sclerosis Obesity At the forefront of health innovation, our organization is dedicated to creating and refining standards that stay on the cutting edge, using an evidence-based approach. Through the years, he discovered other biotoxin illness in people who have had exposure to the following: Water-damaged buildings (WDB): WDBs are often hotspots for mold, even if you can’t see it or smell it. The VCS test has 92% accuracy rate based on data collected from tens of thousands of tests taken over the years since Dr. And as far as unveiling the complexity of chronic inflammatory response syndrome goes, he will keep looking for a cure. com Biotoxin-Associated Illnesses Potential for exposure to biologically produced neurotoxins Multiple Dr. 5% chance the person has CIRS. have dysregulated hypotension, in ADH/ VCS, osmolal and eradication After mold of Looking for a structured understanding of Dr. When molds grow in indoor environments, they have the potential to produce mycotoxins—potent Biotoxin Illness Pathway 4 Main Ways MARCONS Harm the Immune System MARCoNS release Exotoxins A and B, damaging alpha MSH by splitting it MARCoNS colonize and produce a matrix. The information there is invaluable. His “Biotoxin Pathway” and treatment protocol have been instrumental pieces of the puzzle for many struggling with chronic biotoxin illness. Start listening today for free! The Shoemaker Protocol is a step-by-step treatment framework for CIRS. Jan 8, 2019 · In part 2 of a series on Mold-Related Biotoxin Illness (or Chronic Inflammatory Response Syndrome), Dr. Mar 29, 2024 · CIRS and the Biotoxin Pathway Understanding the intricate relationship between Chronic Inflammatory Response Syndrome (CIRS) and the biotoxin pathway is important for anyone exploring this complex health condition. Shoemaker lecture on CIRS and the biotoxin pathway, it resonated with her. Here you will find reputable links to biotoxin illness resources outside of Mold Free Menu. A list of possible causes of CIRS from biotoxin exposure. Bloodwork Mold Home Testing Mind-Body Healing Where to find an IEP and CIRS Practitioner If this resource helps you, please share so that others can heal. Hartman reviews the systematic criteria used to diagnose CIRS. Discover the Shoemaker process and protocol for diagnosing, testing and treating Mold Illness. If you want to do a deep dive on systemic impacts, search “Dr Shoemaker’s Biotoxin Pathway”. “Shoemaker subsequently mapped out the pathways involved in CIRS and developed a case definition for the condition. While illness acquired following exposure to the interior The following model describes modes of action along a pathway leading to biotoxin- associated illness for the purpose of organizing current knowledge into testable hypotheses. Unhealthy Buildings and Mold Outbreaks Hope, and Healings, Mold illness, CIRS, PANS, PANDAS, anxiety, depression, ADHD, biotoxin, Lyme disease, Bartonella, Babesia, tick infections, detoxification, immune High cytokine levels in the capillaries attract white blood cells, leading to restricted blood flow, and lower oxygen levels. Dive into the intricate world of mold toxicity and Chronic Inflammatory Response Syndrome (CIRS) with Amanda Hoelscher, APRN, AGNP. In genetically susceptible people, biotoxins bind to pattern receptors, Back to Resources Biotoxin Pathway Holds Key Pieces of Puzzle in Solving Chronic Illness Chronic illnesses often seem like complex puzzles where it quickly becomes evident that many of the pieces are missing. The biotoxin-driven multisystem, multisymptom pathway imbalance persists until the culprit biotoxins are effectively cleared from the body and the neuroimmune, vascular, and endocrine imbalances are corrected. Correcting toxin carriage in the body with CSM (Cholestyramine) or Welchol, using VCS monitoring to assess progress 3. Shoemaker’s daily practice, other illnesses caused by exposure to Dec 21, 2020 · Toxicology and Industrial Health, 25 (9-10), 669-680. In genetically susceptible people, biotoxins bind to pattern receptors, 3. Dr Shoemaker's information on diagnosis, treatment, resources, book, and more. What Are the Symptom Clusters for CIRS? Since CIRS symptoms often overlap with other conditions, this symptom cluster list helps provide better diagnostic Ritchie Shoemaker's 4 research works with 1 reads, including: The Evolution of Chronic Inflammatory Response Syndrome (CIRS) and the Biotoxin Pathway Jul 12, 2015 · The phenomenon of “Mold Ilness” has gained increased attention in the past year, but the condition is not new. The mycotoxin connection to chronic inflammatory illness is finally being established. Ritchie Shoemaker has significantly contributed to the field of CIRS through his pioneering work on the Biotoxin Pathway. The toxins attach to the immune system to trigger an inflammatory response and induce hormonal changes. This barrier blocks immune cells from removing them MARCoNS can Author Information Ritchie C. Peer reviewed journals and more for CIRS, mould allergy, water-damaged buildings. Ritchie C. The Biotoxin Pathway. It is also known as biotoxin Illness, mold illness, and mold toxicity. Shoemaker, the pioneer of biotoxin illness, the Shoemaker protocol is a multi-step treatment protocol that addresses all the downstream effects of the biotoxin pathway. Chronic Inflammatory Response Syndrome (CIRS) is a condition discovered and researched by Dr. Will this work? ANSWER: No. Here is Dr. Biotoxin illness recovery requires addressing the entire Biotoxin Pathway, not just symptom management. The implications for the prevention and treatment of chronic inflammatory The Biotoxin Pathway High cytokine levels in the capillaries attract white blood cells, leading to restricted blood flow, and lower Capillaries oxygen levels. His protocol brought hope to patients who felt unseen and unwell for too long. Editor’s Note: Exposure to mold in water-damaged Dec 4, 2004 · Sick Building Syndrome: Another Stop Along the Biotoxin Pathway 2004 (71 Slides) Maryland College of Occupational and Environmental Medicine, Johns Hopkins 12/04/2004 Ritchie D. Jun 3, 2024 · Dr. THE 12-STEP SHOEMAKER PROTOCOL OVERVIEW The protocol used in the treatment of mold illness is straight forward, but there are a series of steps to be taken, each in its proper order. , mold, bacteria, Lyme) initiate a cascade of immune responses, particularly when the individual has the HLA-DR/DQ genetic mutation that hampers the Oct 30, 2014 · Shoemaker’s Mold Contributions Ritchie C. ppt Author Jodi Ashcraft Created Date Sep 11, 2024 · Today's guest is Dr. Shoemaker, a leading figure in the study of biotoxin-related illnesses, this comprehensive multi-step treatment plan effectively tackles the wide-ranging consequences of the biotoxin pathway. No matter how hard we try to understand exactly what is causing us to be ill, a full understanding seems to often be evasive. Prolonged Illness c R. April Vukelic, DO-Mechanisms of potential Central Nervous System injury in Chronic Inflammatory Response SyndromeApril Vukelic, DO Membership grants you access to the world's leading experts on biotoxin related illness, allowing you to submit questions to our Shoemaker Certified Physicians. 3. Dec 5, 2024 · It was just a year earlier that he had met Ritchie Shoemaker, when Ritchie had given a talk on his latest findings and a novel flow chart of pathology he called the “Biotoxin Pathway”. Overview, Diagnosis, and Treatment This paper reviews a recently discovered chronic biotoxin illness that affects as many as one in four people in the United States and elsewhere. Andy Heyman, M. " Looking for a structured understanding of Dr. 5. Jan 13, 2021 · In Episode #44, Dr. D. Ritchie Shoemaker, for treating mold llness and CIRS. 4. For a more detailed understanding of CIRS, click here. What Is Visual Contrast Sensitivity (VCS) The Visual Contrast Sensitivity (VCS) test is a measure of the neurological function of vision called visual contrast. Shoemaker's excellent biotoxin pathway picture which helps elucidate what is going on. Treatment for symptoms of mold exposure includes using CSM (Cholestyramine) and then eradicating biofilm-forming “MARCoNS” with antibiotics. His grasp of the biotoxin pathway and the clarity it brings to our understanding these illnesses has brought healing to thousands of suffering patients. In genetically susceptible people, biotoxins bind to pattern receptors, The biotoxin binds to surface receptors (Toll receptors and many more) in nearly every cell in the body. Ritchie Shoemaker to address CIRS and other biotoxin-related illnesses. Genetic Link to Mold Related Illness The Biotoxin Pathway illustrates that if you are genetically predisposed to biotoxin illness (HLA susceptible) your chances of having a mold illness (or other biotoxin illness) goes up enormously. Richie Shoemaker CIRS Connected This is a blog by Tonia Fleming to contact me email toniacalway @ gmail. Learn about the causes, symptoms, and treatment options for this condition. Shoemaker’s protocol first – going after MARCoNS is step three. Shoemaker discovered the biotoxin pathway. Dr. This combination is a rare find and often critical to unlayering the issues that must be explored to recover health. Dr Ritchie Shoemaker The Shoemaker Protocol has been used for nearly 3 decades, having been through several revisions. Reduced VEGF leads to fatigue, muscle cramps, and shortness of breath (may be over-ridden by replacement with erythropoietin). The CIRS protocol developed by Dr. Removal from prior exposure (this means no more working, schooling, or living in a moldy environment for WDB illness patients) 2. After sharing a conversation about the effects of ciguatoxins, Ritchie and Jimmy started a collaborative effort. By reading Mold Warriors, you will learn how to use the Biotoxin Pathway, a magnificent scientific and medical breakthrough, to then easily recognize and treat the mold illness, leaving behind meaningless diagnoses such as fibromyalgia, chronic fatigue, stress, “chronic pain syndrome,” deconditioning and more. Sep 26, 2022 · Dr. The concept of the ―final common pathway,‖ began to emerge following the 2010 Physician Consensus Statement (15) in which this inflammatory illness finally was named chronic inflammatory response syndrome (CIRS). Carlson’s key leading physicians he has built his own method from, has done a fantastic job outlining just exactly what toxic mold can Developed by Dr. 0 "The mystery illnesses of chronic fatigue syndrome, Lyme disease, fibromyalgia, adult depression, POTS, adult asthma and many other disabling conditions are understood once we piece together the ingenious Biotoxin Pathway that Dr Shoemaker has painstakingly discovered for us. Detection of Mycotoxins in Patients with Chronic Fatigue Syndrome. With his permission, you can view hist recent Biotoxin Pathway 2. Berndtson Biotoxin CIRS Help Toxic Mould Support Australia The Shoemaker Protocol™ Visual Contrast Sensitivity Test (VCS) Convenient, affordable, reliable. To view it as a PDF, click the image below. Liver mixes with bile. Shoemaker's work. The Biotoxin Pathway According to a growing body of evidence in peer reviewed studies biotoxin exposure can contribute to significant changes in health for many at-risk people. The Biotoxin Pathway For a better understanding of chronic inflammatory response syndrome, Dr. It provides a roadmap to recovery and has been praised for its effectiveness. Shoemaker treatment headaches, ity corrects ity . He has identified and documented the etiology, physiological dysregulation, objective clinical manifestations, specific Apr 1, 2022 · Mold Illness - Overview of the Biotoxin Pathway with Dr Eric Dorninger Vitality Hour Clips 62 subscribers Subscribed Jan 27, 2023 · Symptoms of CIRS and the Impact on the Immune System keywords: cirs symptoms, autoimmune diseases, Biotoxin pathway, shoemaker CIRS is one of the most common causes of autoimmune diseases. Jill Interviews Dr. How Dr. The treatment of choice for CIRS is Dr. However, it's important to note that CIRS can also be caused by biotoxin producers such as cyanobacteria and a marine dinoflagellate that produces the Ciguatera toxin found in certain types of fish. Shoemaker MD deserves tremendous credit for being the voice that brought mold illness to our awareness. Access to members-only special offers and other free materials. What is the mechanism of CIRS? The diagram below is the Biotoxin Pathway Made Simple which is adapted from Dr. The Shoemaker Protocol™ VCS testing system is an extremely valuable tool to detect and monitor exposure to toxic environments for individuals with CIRS. Shoemaker and colleagues are generating a database of differential gene activation that will be a fingerprint for biotoxin illness and will help differentiate the root cause precipitating the Biotoxin Pathway. Buy videos of Dr. Ritchie Shoemaker giving presentations on biotoxin illness. Ritchie Shoemaker, MD's "Biotoxin Pathway" To view the article, click the article name link above or click here. When indicated, we use a detailed clinical history and specialized labs to evaluate exposure and immune reactivity. Shoemaker, with in depth details on the pathophysiology for each step. smolal serum sodium and osmolality. Ritchie Shoemaker to address CIRS. This protocol is the only peer-reviewed and clinically supported approach for treating biotoxin illness, including mold-related conditions. Thanks. Using various tests, Dr. Jun 11, 2025 · June 11, 2025 Chronic Inflammatory Response Syndrome (CIRS): Causes, Symptoms & Functional Medicine Treatment Chronic Inflammatory Response Syndrome (CIRS) is a complex illness caused by biotoxin exposure. Shoemaker has mapped out the Biotoxin-Related Illness Pathway that helps identify and correct dysfunction for those made ill by neurotoxins from mold, lyme disease, spider bites, and other bacteria and fungi. Toxins 2013:605-617. shortness of breath Based on work written by: H Kenneth Hudnell, PhD, Research Director Ritchie Shoemaker, MD, Medical Director Publication in the peer-reviewed literature is essential for advancing the mission of the Center for Research on Biotoxin Associated illnesses (CRBAI). Read more about treatment for CIRS from Flourish Clinic today! Jan 22, 2025 · Ritchie Shoemaker, MD is a recognized leader in patient care, research, and an education pioneer in the field of biotoxin related illness. Ricky Shoemaker MD. Based on genetics research, we know that 24% of the population has the genetic profile that makes them susceptible to developing a biotoxin or mold-related illness whereas the other 76% of the population will generally be able to detoxity biotoxins and avoid creating the Biotoxin Pathway that leads to multple disease processes. Shoemaker has published without being creative or substituting favorite unproven ideas in place of those proven to work. Do you think, or has Shoemaker said, that Lyme disease without Biotoxin illness can cause a lowered MSH? I don’t have any pain or reduced pain tolerance but this high MARCoNS result might be a low MSH indication. Take the VCS any time you question possible mold exposure. They too, can develop significant biotoxin-related health p including inflammation and metabolism. Shoemaker MD Medical Director, Center for Research on Biotoxin Associated Illnesses David Lark Mycologist, MouldLabs, Australia James C. So I read the book and got to the point where Dr. 0 presentation slides by clicking on the image below. Shoemaker's work on CIRS (Chronic Inflammatory Response Syndrome)? A wonderful resource for patients and physicians alike, A Physician’s Guide to Understanding & Treating Biotoxin Illness Based on the work of Ritchie Shoemaker, M. Ritchie Shoemaker, MD's "Biotoxin Pathway" Having retired from practice in January, Dr. Who is Dr. It focuses on removing ongoing exposure, supporting detox pathways, restoring energy production, and correcting imbalances. Biotoxin illness or Chronic Inflammatory Response Syndrome (CIRS) is a chronic inflammatory condition involving primarily the innate immune system which results from exposure to a biotoxin (ie: mycotoxins from mold or toxins produced by bacteria such as Borrelia burgdorferi from Lyme disease). Ritchie Shoemaker is a recognized leader in patient care, research, and an education pioneer in the field of biotoxin-related illness. I immediately realized that Ritchie had discovered the entire mechanism by which these toxins affect our health. The inability to process toxins, regardless of source, leads to a series of biochemical alterations called the Biotoxin Pathway. The protocol has been graphically represented in a pyramid containing the 11 steps of the treatment pathway. nih. The proper definition of Chronic Inflammatory Response Syndrome (CIRS) is “An acute and chronic, systemic inflammatory response syndrome acquired following exposure to the interior environment of a water-damaged building (WDB) with resident toxigenic organisms, including, but not Biotoxin Illness Pathway 4 Main Ways MARCoNS Harm the Immune System 2 1 MARCoNS release Oct 29, 2016 · He is a Shoemaker-certified CIRS doctor in addition to his work with Lyme disease. Eradicating biofilm-forming MARCoNS 4. These two main body systems interact in countless ways creating the symptoms and the proteomics (lab abnormalities) tha Article: Biotoxin Pathway Holds Key Pieces of Puzzle in Solving Chronic IllnessPublication: Public Health Alert / June 2007 Summary: A look at Dr. While illness acquired following exposure to the interior environment of water-damaged buildings (WDB) comprises the bulk of Shoemaker’s daily practice, other illnesses caused by exposure to biologically produced toxins are quite … Mar 16, 2025 · CellCore’s Biotoxin Binder uses cholestyramine’s superior binding capacity compared to alternatives. Interactive animation of the structure of ATP Adenosine triphosphate (ATP) is a nucleotide triphosphate [2] that provides energy to drive and support many processes in living cells, such as muscle contraction, nerve impulse propagation, and chemical synthesis. Ritchie Shoemaker Mold Toxicity CIRS – Overview, Diagnosis, and Treatment by Dr. The labs are monitored (MMP9, VEGF, C4a, and TGF beta-1) and Visual Contrast Sensitivity (VCS) at each step. High cytokine levels in the capillaries attract white The Biotoxin Pathway Capillaries blood cells, leading to restricted blood flow, and lower oxygen levels. These certified mold doctors are the first in the world to achieve certification in the Shoemaker Protocol mold sickness treatment regime. Ritchie Shoemaker’s 11 Step Biotoxin Removal Protocol (see figure 1). The CIRS protocol contains multiple steps that address each corresponding stage of the biotoxin pathway in order to correct all consequences of toxic mold exposure. The biotoxin binds to surface receptors (Toll receptors and many more) in nearly every cell in the body. [3 The Biotoxin Pathway Perhaps of the greatest diagnostic and therapeutic importance is the finding of a marked suppression of 1) ribosomal; and 2) nuclear encoded mitochondrial genes in CIRS patients before treatment. Shoemaker's new web site SurvivingMold. Brewer J, Thrasher J, Hooper D. Cholestyramine (CSM) is a resin which has been historically used for lowering cholesterol. She went to hear Dr. 2004 (71 Slides) Maryland College of Occupational and Environmental Medicine, Johns Hopkins 12/04/2004 Ritchie D. Shoemaker MD Chronic Fatigue Center 500 Market St. extended information concerning the specific area designated explanation of acronymns and terms for the specific area Note: Most of the extended information, explanation, and definitions described immediately above were taken from Wikipedia, and from the writings of Dr. and that labs static 60% but shocking of also Biotoxin polydipsia, that Illness patient’s polyuria, orthostatic patients experience. (2020, March 3). Nov 17, 2020 · Science supporting Mould Illness/CIRS. com Center for Research on Biotoxin-Associated Illnesses 501 (c) 3 non-profit research organization www. is packed with colorful diagrams and tables for easier understanding of this complex information. Nasal shoemaker • • • touCA"OS • The Biotoxin Pathway Capillaries oktnes High cytokine levels in the capillaries attract white blood cells, leading to restricted blood flow, and lower oxygen levels. . Step two is to be on cholestyramine for at least one month before treating MARCoNS. This decline occurs because biotoxins can disrupt neurological and visual pathways, including those related to retinal and cortical function. Biotoxins are toxins created by living organisms. One doesn’t acquire biotoxin illness with short-term exposure; it develops over time. Shoemaker has appeared on numerous television and radio shows, received many awards, and has a long list of Sep 13, 2009 · The “Biotoxin Pathway” shows the cascade of events that starts a biotoxin illness in those who are HLA-susceptible the moment that they are exposed to a biotoxin. Research has shown that people suffering from CIRS and other biotoxin-related illnesses often experience a measurable decline in this ability—even before other symptoms become severe. [0:55:33] SCOTT: Just then to clarify, if we look at the Rosetta Stone today for HLA-DR, we don't see Actinos, endos, beta-glucans, we don't see any of those things. Ritchie Shoemaker. A review of the "Biotoxin Pathway," discovered by Dr. Shoemaker and why is it important to use a shoemaker practitioner? Ritchie Shoemaker, M. Mold Illness Treatment - Step By Step 1. chronicneurotoxins. Shoemaker is now focusing on certifying physicians as experts, expanding the use of the genomic aspects of biotoxin illness, and publishing information stored in countless datasets. bsmqx nvjm ozwgkt nswzd yrs a7mb ncmv oo2t hwoc wlte